Paper ID | BIO-3.9 | ||
Paper Title | KINET: A NON-INVASIVE METHOD FOR PREDICTING KI67 INDEX OF GLIOMA | ||
Authors | Xuhui Li, Yong Xu, Central South University, China; Feng Xiang, Qing Liu, Xiangya Hospital of Central South University, China; Weihong Huang, Mobile Health Ministry of Education-China Mobile Joint Laboratory, China; Bin Xie, Central South University, Hunan Xiangjiang Artificial Intelligence Academy, China | ||
Session | BIO-3: Biomedical Signal Processing 3 | ||
Location | Area C | ||
Session Time: | Wednesday, 22 September, 14:30 - 16:00 | ||
Presentation Time: | Wednesday, 22 September, 14:30 - 16:00 | ||
Presentation | Poster | ||
Topic | Biomedical Signal Processing: Medical image analysis | ||
IEEE Xplore Open Preview | Click here to view in IEEE Xplore | ||
Abstract | In this paper, a multimodal magnetic resonance imaging (MRI) and heterogeneous metadata (including age, gender) dataset containing 263 patients was established. Based on this dataset, a new multimodal deep neural network (KiNet) was proposed, aiming to effectively predict the Ki67 index in gliomas in a non-invasive way by fusing multimodal MRI features and metadata. We adopted a five-fold cross-validation approach to verify the performance of the network. KiNet achieved results with an AUC of 0.79 and a kappa coefficient of 0.47. The proposed approach’s outperformance indicated the feasibility of predicting the Ki67 index in gliomas in a non-invasive way. |