Paper ID | TEC-1.6 | ||
Paper Title | LOW-DOSE CT DENOISING USING A STRUCTURE-PRESERVING KERNEL PREDICTION NETWORK | ||
Authors | Lu Xu, The Chinese University of Hong Kong, Hong Kong SAR of China; Yuwei Zhang, Ying Liu, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, China; Daoye Wang, ETH Zurich, Switzerland; Mu Zhou, SenseBrain Technology Limited LLC, United States; Jimmy Ren, SenseTime Research; Qing Yuan Research Institute, Shanghai Jiao Tong University, Hong Kong SAR of China; Jingwei Wei, Institute of Automation, Chinese Academy of Sciences, China; Zhaoxiang Ye, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, China | ||
Session | TEC-1: Restoration and Enhancement 1 | ||
Location | Area G | ||
Session Time: | Tuesday, 21 September, 13:30 - 15:00 | ||
Presentation Time: | Tuesday, 21 September, 13:30 - 15:00 | ||
Presentation | Poster | ||
Topic | Image and Video Processing: Restoration and enhancement | ||
IEEE Xplore Open Preview | Click here to view in IEEE Xplore | ||
Abstract | Low-dose CT has been a key diagnostic imaging modality to reduce the potential risk of radiation overdose to patient health. Despite recent advances, CNN-based approaches typically apply filters in a spatially invariant way and adopt similar pixel-level losses, which treat all regions of the CT image equally and can be inefficient when fine-grained structures coexist with non-uniformly distributed noises. To address this issue, we propose a Structure-preserving Kernel Prediction Network (StructKPN) that combines the kernel prediction network with a structure-aware loss function that utilizes the pixel gradient statistics and guides the model towards spatially-variant filters that enhance noise removal, prevent over-smoothing and preserve detailed structures for different regions in CT imaging. Extensive experiments demonstrated that our approach achieved superior performance on both synthetic and non-synthetic datasets, and better preserves structures that are highly desired in clinical screening and low-dose protocol optimization. |